Medullar Transplant Department

Medullar Transplant and Hematopoietic Stem Cell Department was founded in 2002. This is where, in June 2001, an autologus medular transplant  (national premiere) and in January 2003 an allogenic medullar transplant were performed. This Department became a member of EBMT in 2001.

The Department contains:

  • 5 hospital beds (2 sterile rooms; 1 room fitted with a HEPA filter and positive pressure; 2 “clean” rooms)
  • 5 day-admission beds

Our department has access to:

  • hematology, biochemistry, bacteriology, immunology laboratories
  • flowcitometry laboratory
  • cytogenetics laboratory
  • pathology laboratory
  • transfusion and hemobiology unit
  • criopreservation unit
  • radiology and irradiated blood-products service
  • psychology and psychotherapy

Our Department is cooperating with:

  • The Immunology Center of County Hospital No 1 Timis
  • HLA Laboratory

Team Members

  • Prof. Dr. Serban Margit – primary pediatrician, primary hematologist, primary oncologist, primary immunologist
  • Ass. Prof. Dr. Smaranda Arghirescu – primary pediatrician, specialist in medical oncology
  • Dr. Claudiu Plesa  – hematology specialist, researcher
  • Dr. Radu Firescu  – hematology specialist, researcher
  • Dr. Cristian Jinca  – specialist pediatrician
  • Dr. Mihaela Lesovici – specialist microbiologist
  • Dr. Mihaela Baica – laboratory medicine specialist
  • Dr. Mihaela Lelik – hematology – laboratory specialist
  • Dr. Marioara Pacuraru – primary radiologist
  • Dr. Andrada Oprisoni – doctorand
  • Dr. Loredana Stana  – doctorand
  • Dr. Florin Frunza  – emergency medicine specialist, doctorand
  • Laura Jinca – psychologist
  • Rodica Ilie – primary pathologist

Perfecting stages:  ( 2-24 months) of the transplant team:

Transplant Center – St. Anna Hospital – Vienna (Austria)

  • Prof. Dr. Serban Margit
  • Dr. Adriana Plesa
  • Dr. Claudiu Plesa
  • Dr. Cristian Jinca
  • Dr. Radu Firescu

Transplant Center – Miskolc (Hungary)

  • Prof. Dr. Serban Margit
  • Dr. Cristian Jinca

Transplant Center – Louisville (USA)

  • Prof. Dr. Serban Margit
  • Dr. Adriana Plesa
  • Dr. Claudiu Plesa

Transplant Center – Saint Louis Hospital – Paris (France)

  • Dr. Claudiu Plesa
  • Dr. Adriana Plesa

Transplant Center – Lyon (France)

  • Dr. Claudiu Plesa
  • Dr. Adriana Plesa

Transplant Center Marseille (France)

  • Dr. Radu Firescu

Transplant Center Essen (Germany)

  • Prof. Dr. Serban Margit
  • Dr. Cristian Jinca
  • Dr. Claudiu Plesa
  • Dr. Adriana Plesa

Transplant Center Berlin (Germania)

  • Dr. Mihaela Baica

International collaborations:

  • Transplant center – Miskolc –Prof.Dr. Nagy Kalman
  • Transplant center – Louisville –Prof. Dr. Salvatore Bertolone, Prof.Dr.Rodgers
  • Transplant center – St. Anna Vienna Hospital –Prof. H.Gadner (flowcitrometry, FISH, chimerism)
  • Cancer research center –Viena (Austria) –Prof. T. Lyon (molecular biology)
  • Pathology Institute in Munchen (Germany) –Prof. U. Lohrs (pathology tests and exams)
  • Ludwig Maximilians University of Munich (Germany) –Prof. W. Schramm (HLA biomolecular testing)

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Scientific activity

  • National Congresses: ROMTRANSPLANT – Tg. Mures (2002) – 2 papers, Eforie (2004) – 3 papers,
  • Congres National de Pediatrie – Galati (2005) – 4 papers;
  • Consfatuirea romano-maghiara de oncohematologie pediatrica: Buzias (2003) – 3 papers, Miskolcz (2004) – 2 papers.

International Congresses:

  • EBMT – Montreux (2003) – 1 paper;
  • EBMT – Barcelona (2004) -1 paper;
  • EBMT – Training course 2005 – Budapest -1 paper;
  • EBMT – Paediatric working group Frankfurt 2003 – 2 papers.


  • in extenso: 8
  • abstract:15

Organizational activity

Efforts to attract the financial support necessary for the building of the infrastructure, which unfortunately the Ministry Of Health in Timisoara was unable to supply:

  • treatment and monitoring devices
  • cryopreservation devices
  • building sterile rooms
  • immunology lab
  • cytogenetics lab

Future objectives:

  • reaching 20 marrow transplants in 2006
  • expanding the indications and types of marrow transplants: 2-5 allogenic, the rest autologus.
  • performing an umbilical chord graft transplant.

According to the requirements of the European Society for Blood and Marrow Transplantation (EBMT), it is necessary for a transplant center to perform at least 10 marrow transplants per year so that the cost efficiency ratio allows for full-time transplant team hiring (doctors and nurses) and for the costly devices for the transplant unit and laboratories. In order for this center to be accredited by the EBMT, it must perform at least 10 autologus marrow transplants and at least 10 allogenic marrow transplants per year.